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A UPS Airlines plane crashed in Louisville, Kentucky, killing at least twelve people.
The Paris Agreement, under the United Nations Framework Convention on Climate Change, came into effect.
In the first aviation incident involving an Airbus A380, Qantas Flight 32 suffered an uncontained engine failure and made an emergency landing at Changi Airport in Singapore with no casualties.
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UPS Airlines Flight 2976, a McDonnell Douglas MD-11F crashes into multiple buildings during takeoff at Louisville Muhammad Ali International Airport in Louisville, Kentucky, killing 15 people, including the 3 crew members.
The Khash massacre, which refers to the repression of protesters by Iranian security forces, resulting in 18 deaths and more than 20 injuries.
The Tigray War begins with Tigrayan rebels launching attacks on Ethiopian command centers.
A cargo plane crashes shortly after takeoff from Juba International Airport in Juba, South Sudan, killing at least 37 people.
A building collapses in the Pakistani city of Lahore resulting in at least 45 deaths and at least 100 injuries.
Aero Caribbean Flight 883 crashes into Guasimal, Sancti Spíritus; all 68 passengers and crew are killed.
Qantas Flight 32, an Airbus A380, suffers an uncontained engine failure over Indonesia shortly after taking off from Singapore, crippling the jet. The crew manage to safely return to Singapore, saving all 469 passengers and crew.
Barack Obama becomes the first person of biracial or African-American descent to be elected as President of the United States.
Chinese authorities arrest cyber-dissident He Depu for signing a pro-democracy letter to the 16th Communist Party Congress.
Israel-Palestinian conflict: Israeli prime minister Yitzhak Rabin is assassinated by an extremist Israeli.
China Airlines Flight 605, a brand-new 747-400, overruns the runway at Hong Kong Kai Tak Airport.
Ronald Reagan is elected as the 40th President of the United States, defeating incumbent Jimmy Carter.
Iran hostage crisis: A group of Iranian college students overruns the U.S. embassy in Tehran and takes 90 hostages.
The Netherlands experiences the first car-free Sunday caused by the 1973 oil crisis. Highways are used only by cyclists and roller skaters.
Vietnam War: The United States turns over control of the air base at Bình Thủy in the Mekong Delta to South Vietnam.
Salvador Allende takes office as President of Chile, the first Marxist to become president of a Latin American country through open elections.
Iberia Flight 062 crashes in Blackdown, West Sussex, killing all 37 people on board including British actress June Thorburn.
The Arno River floods Florence, Italy, to a maximum depth of 6.7 m (22 ft), leaving thousands homeless and destroying millions of masterpieces of art and rare books. Venice is also submerged on the same day at its record all-time acqua alta of 194 cm (76 in).
The United States concludes Operation Fishbowl, its final above-ground nuclear weapons testing series, in anticipation of the 1963 Partial Nuclear Test Ban Treaty.
At the Kasakela Chimpanzee Community in Tanzania, Jane Goodall observes chimpanzees creating tools, the first-ever observation in non-human animals.
Soviet troops enter Hungary to end the Hungarian revolution against the Soviet Union that started on October 23. Thousands are killed, more are wounded, and nearly a quarter million leave the country.
The United States government establishes the National Security Agency, or NSA.
World War II: The 7th Macedonian Liberation Brigade liberates Bitola for the Allies.
World War II: Operation Pheasant, an Allied offensive to liberate North Brabant in the Netherlands, ends successfully.
World War II: Disobeying a direct order by Adolf Hitler, General Field Marshal Erwin Rommel begins a retreat of his forces after a costly defeat during the Second Battle of El Alamein. The retreat would ultimately last five months.
World War II: U.S. president Franklin D. Roosevelt orders the United States Customs Service to implement the Neutrality Act of 1939, allowing cash-and-carry purchases of weapons by belligerents.
Spanish Civil War: Largo Caballero reshuffles his war cabinet, persuading the anarcho-syndicalist CNT to join the government.
Nellie Tayloe Ross of Wyoming becomes the first female elected as governor in the United States.
In Egypt, British archaeologist Howard Carter and his men find the entrance to Tutankhamun's tomb in the Valley of the Kings.
The Saalschutz Abteilung (hall defense detachment) of the Nazi Party is renamed the Sturmabteilung (storm detachment) after a large riot in Munich.
Japanese prime minister Hara Takashi is assassinated in Tokyo.
World War I: The Armistice of Villa Giusti between Italy and Austria-Hungary is implemented.
City and South London Railway: London's first deep-level tube railway opens between King William Street and Stockwell.
Camagüey, Cuba, revolts against Spain during the Ten Years' War.
American Civil War: Confederate troops bombard a Union supply base and destroy millions of dollars in materiel at the Battle of Johnsonville.
Camillo Benso, Count of Cavour, becomes the prime minister of Piedmont-Sardinia, which soon expands to become Italy.
Sir James Young Simpson, a Scottish physician, discovers the anaesthetic properties of chloroform.
Newport Rising: The last large-scale armed rebellion against authority in mainland Britain.
The Russo-Ottoman siege of Corfu begins.
Northwest Indian War: The Western Confederacy of American Indians wins a major victory over the United States in the Battle of the Wabash.
Wolfgang Amadeus Mozart's Symphony No. 36 is performed for the first time in Linz, Austria.
The Rebellion of Túpac Amaru II against Spanish rule in the Viceroyalty of Peru begins.
The Teatro di San Carlo, the oldest working opera house in Europe, is inaugurated in Naples, Italy.
The future Mary II of England marries William, Prince of Orange; they later jointly reign as William and Mary.
Eighty Years' War: In Flanders, Spain captures Antwerp (which is nearly destroyed after three days).
Catherine of Aragon (later Henry VIII's first wife) meets Arthur Tudor, Henry VIII's older brother – they would later marry.
Christopher Columbus reaches the Leeward Islands.
Armagnac–Burgundian Civil War: Joan of Arc liberates Saint-Pierre-le-Moûtier.
War of the Straits: The Genoese fleet under Paganino Doria defeats and captures the entire Venetian fleet under Niccolò Pisani at the Battle of Sapienza.
Following Byzantine emperor Anastasius' deposition of Chalcedonian patriarchs and attempts to make Monophysite changes to liturgy, riots break out in Constantinople with a mob trying to proclaim Areobindus as emperor.